Rice University has received an award from the National Science Foundation that will help researchers develop a platform technology for non-invasive diagnostic testing. The team, comprised of co-investigators from Rice University, Harvard, MIT, Carnegie Mellon and Cornell University, will use the $10 million to create wearable and point-of-care microscopes for in-vivo, 3-D tissue imaging below the skin’s surface.
“Imagine a wearable device no larger than a watch that uses sensors to continuously measure white blood cell count and wirelessly communicate with the oncologist’s office,” said Ashutosh Sabharwal, principal investigator and professor at Rice University, in a university press release. “The patient could go about their daily life. They’d only have to go to the hospital if there was a problem.”
The technology will use computational scatterography, a combination of mathematical algorithms, camera design and imaging sensors that will allow them to reverse engineer the scattered light path. “If we succeed, this isn’t just one product,” said Sabharwal. “It’s a platform technology that will be able spinoff into many products that can be used in the care of nearly 100 health conditions.”
Tonometry-derived features showed superior performance compared to other feature groups and baselines, while younger and normotensive subjects had the most consistent readings across all feature groups.
The long-awaited part 23 of ISO 10993, the series of standards governing Biological Evaluation of Medical Devices, was published in January 2021. It was the first to introduce validated methods for in-vitro irritation tests. This article reviews the latest developments…
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